BC Innovations | Jan 7, 2016
Distillery Therapeutics

Therapeutics: P. falciparum plasmepsin I; P. falciparum plasmepsin II; P. falciparum plasmepsin IV

Infectious disease INDICATION: Malaria Cell culture studies identified aminoquinazolinone-based inhibitors of Plasmodium falciparum plasmepsins I, II and IV that could help treat malaria. Chemical synthesis and in vitro testing of aminoquinazolinone analogs yielded multiple compounds...
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