BioCentury | Jul 11, 2013
Distillery Therapeutics

Indication: Infectious disease

...and cell culture studies suggest disrupting the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1...
...malaria. In an in vitro screen, EPCR was found to interact with a form of PfEMP1...
...domain cassette 8 (DC8) variant, which is associated with severe malaria. In vitro, parasites expressing DC8-PfEMP1...
BioCentury | Apr 23, 2009
Targets & Mechanisms

New fronts against malaria

...amongst PfEMP1 variants is a key mechanism of immune evasion by P. falciparum , and PfEMP1...
BioCentury | Apr 23, 2009
Distillery Therapeutics

Indication: Infectious disease

...Publication and contact information Infectious disease Malaria Plasmodium falciparum sirtuin 2 (PF13_0152; Sir2); P. falciparum erythrocyte membrane protein 1 (VAR; PfEMP1...
...less switching in expression of the parasite's 60 variants of PfEMP1 than wild-type P. falciparum. PfEMP1...
BioCentury | Mar 28, 2005
Product Development

Tilting at windmills

...taking the same approach to a malaria vaccine: creating a multivalent immunogen based on the PFEMP1...
BioCentury | Mar 25, 2002
Company News

National Institute of Allergy and Infectious Diseases other research news

...not provide protection when the monkeys were challenged with a malaria strain expressing a variant PfEMP1...
...Infectious Diseases , Bethesda, Md. Product: y179 peptide mimic of the CD36 binding region of P. falciparum erythrocyte membrane protein 1 (PfEMP1)...
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