BC Innovations | Jul 11, 2013
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Endothelial protein C receptor (EPCR) In vitro and cell culture studies suggest disrupting the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)...
BC Innovations | Apr 23, 2009
Targets & Mechanisms

New fronts against malaria

A key challenge in combating malaria is the rapid development of resistance that Plasmodium falciparum parasites mount against older drugs. Now, a pair of articles describes two new ways to attack the infection: inhibiting host...
BC Innovations | Apr 23, 2009
Distillery Therapeutics

Indication: Infectious disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Plasmodium falciparum sirtuin 2 (PF13_0152; Sir2); P. falciparum erythrocyte membrane protein 1 (VAR; PfEMP1) Studies in cell culture suggest...
BioCentury | Mar 28, 2005
Product Development

Tilting at windmills

Third World Solutions Tilting at windmills The experience of Maxygen Inc. in monetizing the various applications of its directed evolution platform perfectly illustrates the problems companies encounter when they try to commercialize vaccines, even with...
BC Week In Review | Mar 25, 2002
Company News

National Institute of Allergy and Infectious Diseases other research news

Researchers published in the Proceedings of the National Academy of Sciences evidence that y179 could be used as a malaria vaccine. In 6 monkeys vaccinated with y179 plus complete Freund's adjuvant (FA), 0 monkeys developed...
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