BioCentury | Sep 29, 2016
Targets & Mechanisms

Hitting for the cycle

...derivatives of approved drugs. GlaxoSmithKline plc has GSK932121 , an electron transport chain inhibitor of CYTB...
...Diego, La Jolla, Calif. Vertex Pharmaceuticals Inc. (NASDAQ:VRTX), Boston, Mass. Targets and Compounds CYTB - P. falciparum cytochrome B...
BioCentury | Jan 12, 2012
Distillery Therapeutics

Indication: Infectious disease

...Summary Licensing status Publication and contact information Infectious disease Malaria P. falciparum cytochrome b (CYTB) In vitro studies identified CYTB...
...treat malaria. SAR studies and enzymatic assays identified a class of tetracyclic benzothiazepines that inhibited CYTB...
...vitro, the compounds decreased proliferation of Plasmodium falciparum strains, including those resistant to the generic CYTB...
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