07:00 , Oct 13, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Oxysterol binding protein 2 (OSBP2; ORP4)

Cancer INDICATION: Acute lymphoblastic leukemia (ALL) Cell culture and mouse studies suggest inhibiting OSBP2 could help treat T cell ALL. In a human T cell ALL cell line, shRNA targeting OSBP2 decreased survival compared with scrambled shRNA....
08:00 , Feb 12, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Oxysterol binding protein (OSBP); oxysterol binding protein 2 (OSBP2; ORP4)

Infectious disease INDICATION: Viral infection In vitro studies suggest the generic antifungal drug itraconazole could help treat picornaviral and hepatitis C viral (HCV) infection. In human cells infected with a panel of enteroviruses and other picornaviruses, itraconazole...