BioCentury | Apr 18, 2017
Distillery Therapeutics

Cancer

...INDICATION: Colorectal cancer; breast cancer Cell culture and mouse studies suggest inhibiting OGDH could help treat...
...growth. Next steps include identifying and testing OGDH inhibitors. TARGET/MARKER/PATHWAY: Oxoglutarate α-ketoglutarate dehydrogenase lipoamide (OGDH; OGDC...
...Hahn, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass. email: william_hahn@dfci.harvard.edu Hongjiang Li Dana-Farber Cancer Institute Oxoglutarate alpha-ketoglutarate dehydrogenase lipoamide (OGDH) (OGDC) Phosphoinositide...
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