23:04 , Oct 26, 2018 |  BC Extra  |  Politics & Policy

FDA grants first qualification of a clinical safety biomarker

FDA qualified a group of kidney injury biomarkers from the Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium (BC) and the Critical Path Institute (C-Path) Predictive Safety Testing Consortium (PSTC), marking the first...
19:27 , Sep 10, 2018 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Transgenics and knockouts PGK1-knockout mice expressing an SP-C variant could be used to study the biology of idiopathic pulmonary fibrosis (IPF) and screen for therapies. Mice with inducible knockout of PGK1 that systemically expressed...
21:49 , Aug 29, 2018 |  BC Extra  |  Preclinical News

Sequential therapies trigger axon regeneration in spinal cord injury

University of California Los Angeles and Swiss Federal Institute of Technology Lausanne (EPFL) researchers showed delivery of three sequential therapies could trigger axon growth after complete spinal cord injury in rodents, suggesting the combination approach...
20:11 , Mar 10, 2017 |  BC Week In Review  |  Financial News

TG Therapeutics completes follow-on

On March 9, cancer and autoimmune company TG Therapeutics Inc. (NASDAQ:TGTX) raised $50 million through the sale of 5.1 million shares at $9.75 in a follow-on underwritten by Jefferies, SunTrust, Ladenburg Thalmann, H.C. Wainwright, Aegis...
20:16 , Mar 9, 2017 |  BC Extra  |  Financial News

TG raises $50M in follow-on

TG Therapeutics Inc. (NASDAQ:TGTX) added $1.65 (16%) to $11.80 on Thursday after it raised $50 million through the sale of 5.1 million shares at $9.75 in a follow-on underwritten by Jefferies, SunTrust, Ladenburg Thalmann, H.C....
20:32 , Feb 3, 2017 |  BC Week In Review  |  Financial News

Mustang Bio completes venture financing

Cancer play Mustang Bio Inc. (New York, N.Y.), a subsidiary of Fortress Biotech Inc. (NASDAQ:FBIO, New York, N.Y.), raised $94.5 million in a private placement on Feb. 2. OPN Capital Markets was the placement agent....
23:35 , Feb 2, 2017 |  BC Extra  |  Financial News

Mustang raises $94.5M in private placement

Fortress Biotech Inc. (NASDAQ:FBIO) said its Mustang Bio Inc. (New York, N.Y.) subsidiary raised $94.5 million in a private placement. OPN Capital Markets was the sole placement agent. In May, Mustang said its MB-101 led...
07:00 , Oct 13, 2016 |  BC Innovations  |  Product R&D

Elastic bones

A group at Northwestern University has created a "hyperelastic bone" scaffold to address the need for a bone-inducing material that is easily manufactured, low cost and easy to manipulate during surgery. While the short-term goal...
08:00 , Jan 15, 2015 |  BC Innovations  |  Finance

Consortia cross-talk

There's no doubt that the consortium model is here to stay, but the challenge now is to avoid creating a bureaucracy of committees with duplicate missions and redundancies of effort. The answer might be a...
03:53 , Oct 22, 2014 |  BC Extra  |  Politics & Policy

FDA backs further study of kidney biomarkers

FDA issued its first Letter of Support for two kidney biomarkers identified by the Predictive Safety Testing Consortium (PSTC) of the Critical Path Institute (C-Path). Elevated levels of the two biomarkers, osteopontin (OPN) and neutrophil...