BioCentury | May 28, 2015
Distillery Therapeutics

Therapeutics: TAF12 RNA polymerase II TATA box binding protein (TBP)-associated factor (TAF12); nuclear transcription factor Y γ (NFYC); RAD54-like (RAD54L)

...Cancer INDICATION: Brain cancer Mouse and patient sample studies suggest inhibiting TAF12 , NFYC or RAD54L...
...in 21 genes on chromosome 1. Overexpression of each gene in mouse brains identified TAF12, NFYC...
...shRNA. In the mouse model, orthotopic transplantation of CPC cells pretreated with shRNA against TAF12, NFYC...
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