17:40 , Oct 12, 2017 |  BC Extra  |  Preclinical News

Team describes MECP2 gene therapy approach for Rett syndrome

In a paper published in Nature , researchers at the University of Edinburgh and colleagues showed that adeno-associated virus (AAV) delivery of a shortened version of the methyl CpG binding protein 2 ( MECP2 ;...
21:36 , Dec 16, 2016 |  BC Week In Review  |  Company News

Pacific Biosciences, Roche deal

Roche said it will terminate a 2013 deal to develop and commercialize diagnostics based on Pacific’s Single Molecule Real-Time (SMRT) technology. Roche will have no rights to the technology except for non-exclusive rights to products...
00:00 , Dec 16, 2016 |  BC Extra  |  Company News

Roche ending diagnostics deal with Pacific Biosciences

Pacific Biosciences of California Inc. (NASDAQ:PACB) dropped $3.01 (44%) to $3.89 on Thursday after it said Roche (SIX:ROG; OTCQX:RHHBY) plans to terminate a 2013 deal to develop and commercialize diagnostics based on Pacific’s Single Molecule...
07:00 , Apr 7, 2016 |  BC Innovations  |  Tools & Techniques

Sexy sequencing

Tim Harris, Venture Partner, SV Life Sciences  The days when PhDs were minted based on sequencing a few nucleotides at the end of a piece of nucleic acid are definitely gone. The countless hours spent...
07:00 , May 5, 2014 |  BioCentury  |  Analyst Picks & Changes

Analyst picks & changes

Analyst picks & changes Company Bank Analyst Coverage Opinion Wk chg 5/2cls Alexion Pharmaceuticals Inc. (NASDAQ:ALXN) Bernstein Research Geoffrey Porges Upgrade Outperform (from market perform) 1% $155.12 Porges also raised his target to $193 from...
08:00 , Dec 16, 2013 |  BC Week In Review  |  Company News

Pacific Biosciences, Public Health England, The Wellcome Trust Sanger Institute genomics news

The partners will complete the sequences of 3,000 bacterial genomic strains from Public Health England's National Collection of Type Cultures (NCTC) in a three-year project. The partners will use Pacific Biosciences' Single Molecule, Real-Time (...
08:00 , Dec 12, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Hematology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Hematology Myeloproliferative disorder Retinoic acid receptor (RAR) Mouse studies suggest RAR antagonists could help treat myelofibrosis. Mice with genetic mutations in the...
07:00 , Sep 30, 2013 |  BC Week In Review  |  Company News

Pacific Biosciences, Roche deal

Pacific partnered with Roche's Roche Diagnostics unit to develop diagnostic products, including sequencing systems and consumables, intended for clinical use based on Pacific's Single Molecule Real-Time ( SMRT ) technology. Roche Diagnostics will have exclusive,...
07:00 , Sep 30, 2013 |  BioCentury  |  Finance

Regulatory milestones

Regulatory milestones AMAG Pharmaceuticals Inc. (NASDAQ:AMAG) lost $3.74 (14%) to $22.42 on Wednesday after disclosing that FDA identified "deficiencies" in an sNDA for anemia drug Feraheme ferumoxytol that prevented the agency from discussing potential labeling...
01:11 , Sep 26, 2013 |  BC Extra  |  Company News

Pacific, Roche enter IVD deal

Pacific Biosciences of California Inc. (NASDAQ:PACB) jumped $2.52 (73%) to $5.98 on Wednesday after partnering with Roche Diagnostics to develop diagnostic products, including sequencing systems and consumables, intended for clinical use based on Pacific's Single...