BioCentury | Oct 12, 2017
Preclinical News

Team describes MECP2 gene therapy approach for Rett syndrome

...Rett syndrome-causing missense mutations are concentrated in the methyl CpG binding domain (MBD) and NCoR/ SMRT...
BioCentury | Feb 28, 2017
Distillery Therapeutics

Hepatic

INDICATION: Liver disease Mouse studies suggest inhibiting NCOR1 could help treat neonatal hyperbilirubinemia. In a humanized mouse model of the disease, intestine-specific knockout of NCOR1 decreased total levels of bilirubin in the serum and fat...
BioCentury | Dec 16, 2016
Company News

Roche ending diagnostics deal with Pacific Biosciences

...terminate a 2013 deal to develop and commercialize diagnostics based on Pacific’s Single Molecule Real-Time (SMRT...
BioCentury | Dec 16, 2016
Company News

Pacific Biosciences, Roche deal

...terminate a 2013 deal to develop and commercialize diagnostics based on Pacific’s Single Molecule Real-Time (SMRT...
BioCentury | Apr 7, 2016
Tools & Techniques

Sexy sequencing

...Long-read sequencing (not shown): Pacific Biosciences of California Inc. (NASDAQ:PACB) developed a single-molecule real-time ( SMRT...
BioCentury | May 5, 2014
Analyst Picks & Changes

Analyst picks & changes

...55% growth. Pacific markets the RS II Sequencing System based on its Single Molecule Real-Time (SMRT...
BioCentury | Dec 16, 2013
Company News

Pacific Biosciences, Public Health England, The Wellcome Trust Sanger Institute genomics news

...NCTC) in a three-year project. The partners will use Pacific Biosciences' Single Molecule, Real-Time ( SMRT...
BioCentury | Dec 12, 2013
Distillery Therapeutics

Indication: Hematology

...with genetic mutations in the two receptor binding regions of nuclear receptor co-repressor 2 (NCOR2; SMRT...
...marrow, which is normally repressed by the SMRT-RAR repressor complex. In irradiated mice transplanted with SMRT-mutant...
BioCentury | Sep 30, 2013
Finance

Regulatory milestones

...including sequencing systems and consumables, intended for clinical use based on Pacific's Single Molecule Real-Time (SMRT...
BioCentury | Sep 30, 2013
Company News

Pacific Biosciences, Roche deal

...sequencing systems and consumables, intended for clinical use based on Pacific's Single Molecule Real-Time ( SMRT...
...supply of products to Roche Diagnostics. Perella Weinberg Partners advised Pacific. The biotech said its SMRT...
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