18:21 , Oct 18, 2018 |  BC Innovations  |  Distillery Techniques

Biomarkers; other

TECHNOLOGY: Tissue markers; computational models A computational model based on urine levels of 10 mRNA splice variants could help diagnose DM1. Transcriptomic analysis of cell-free RNA in urine samples from 36 DM1 patients, 28 healthy...
20:45 , Oct 31, 2017 |  BC Innovations  |  Distillery Therapeutics

Musculoskeletal

INDICATION: Muscular dystrophy Mouse studies suggest inhibiting NFIX could help treat Duchenne muscular dystrophy (DMD) and other muscular dystrophies. In tibialis anterior and diaphragm tissue samples from the mdx mouse model of DMD and another...
23:33 , Oct 23, 2017 |  BC Extra  |  Preclinical News

Researchers identify new targets for DMD

Two studies published in Nature Communications show that decreasing expression of nuclear factor I X (NFIX) or sarcolipin (SLN) improves phenotypes associated with Duchenne muscular dystrophy in mouse models of the disease, identifying new targets...
00:28 , Mar 31, 2017 |  BC Innovations  |  Targets & Mechanisms

Cells on the rise

This year’s meeting of the American Association for Cancer Research (AACR) will keep the spotlight on immuno-oncology, where preclinical science is continuing to expand the use of different types of innate and adaptive immune cells...