BioCentury | Nov 13, 2018
Distillery Therapeutics


...include identifying and optimizing BMP6 inhibitors for animal testing. TARGET/MARKER/PATHWAY: Bone morphogenetic protein 6 (BMP6); noggin (NOG)...
...III Health Institute, Madrid, Spain email: Jaime De Leon Carlos III Health Institute Bone morphogenetic protein 6 (BMP6) Noggin (NOG) Alzheimer's...
BioCentury | May 31, 2017
Distillery Techniques

Disease models

...isolated from the small intestine with a cocktail of mouse epidermal growth factor (EGF) , noggin (NOG)...
...sub-family A member 1 (ABCA1) Constitutive androstane receptor (NR1I3) (CAR) Cytochrome P450 Epidermal growth factor (EGF) Liver X receptor (LXR) Noggin (NOG) Peroxisome...
BioCentury | Jan 11, 2017
Distillery Therapeutics


...taken from hairless wounds or dermal wound cells from mice that overexpressed the BMP2/BMP4 antagonist noggin (NOG)...
BioCentury | Feb 18, 2016
Distillery Therapeutics

Therapeutics: Bone morphogenetic protein 2 (BMP2)

...cancer, BMP2 increased proliferation of cells expressing two ovarian cancer stem-like cell (CSC) markers, whereas noggin (NOG)...
BioCentury | Apr 24, 2014
Distillery Therapeutics

Indication: Musculoskeletal disease

...compared with what was seen in wild-type controls. In mice with inactivated notch signaling, recombinant noggin (Nog)...
BioCentury | Oct 24, 2013
Distillery Techniques

Technology: Drug platforms

...into proliferating neuroblasts. In these mice, coexpression of Sox2 with brain-derived neurotrophic factor (Bdnf) and noggin (Nog)...
BioCentury | Jul 11, 2013
Distillery Therapeutics

Indication: Neurology

...Summary Licensing status Publication and contact information Neurology Huntington's disease (HD) Brain-derived neurotrophic factor (BDNF); noggin (NOG)...
BioCentury | Sep 1, 2011
Distillery Therapeutics

Indication: Neurology

...Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology Bone morphogenetic protein 4 (BMP4); noggin (NOG)...
BioCentury | Apr 14, 2011
Distillery Therapeutics

Indication: Autoimmune disease

...that antagonizing BMP4 could help treat MS. In a mouse model of MS, infusion of noggin (Nog)...
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