BioCentury | Jun 13, 2019
Translation in Brief

New inflammasome structure from Harvard, SMOC fodder for rational drug design

...of structures for these have hindered the field, said Wu and Sprott. Targets: NEK7 - NIMA-related kinase...
BioCentury | Jan 29, 2019
Distillery Techniques

Biomarkers

...chromosomal instability, including actin like 6A (ACTL6A), elav like RNA binding protein 1 (ELAVL1) and NIMA-related kinase...
...London, U.K. email: s.janes@ucl.ac.uk Claire Quang University College London Actin like 6A (ACTL6A) Elav like RNA binding protein 1 (ELAVL1) NIMA-related kinase...
BioCentury | Jul 17, 2018
Distillery Therapeutics

Cancer

...the compound in Phase III testing to treat diffuse large B cell lymphoma (DLBCL). TARGET/MARKER/PATHWAY: NIMA-related kinase...
...email: fenghuang-zhan@uiowa.edu Alicia Parker Velcade, bortezomib (LDP-341, MLN341, PS-341) Chinese Academy of Medical Sciences Peking Union Medical College University of Iowa NIMA-related kinase...
BioCentury | Mar 7, 2018
Distillery Therapeutics

Cancer

...cancer and Phase I through Phase II testing for other tumor types and lymphomas. TARGET/MARKER/PATHWAY: NIMA-related kinase...
...MIT and Harvard Washington University School of Medicine in St. Louis Mitogen-activated protein kinase kinase 4 (MKK4) (MAP2K4) NIMA-related kinase...
BioCentury | Dec 7, 2016
Clinical News

GNS identifies disease drivers from CoMMpass data

...maternal embryonic leucine zipper kinase (MELK) ; protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1); and NIMA-related kinase...
BioCentury | Aug 4, 2016
Distillery Techniques

Techniques: Variants and SNPs in four genetic loci as risk markers for amyotrophic lateral sclerosis (ALS)

...ALS cases and 7,315 unaffected volunteers identified association between the disease and loss-of-function mutations on NIMA-related kinase...
BioCentury | Apr 14, 2016
Product R&D

AACR by the numbers

...suggest silencing MMP11 could decrease bladder cancer migration and invasion. Kagoshima University; Chiba University 1105 NIMA-related kinase...
BioCentury | Jun 5, 2014
Distillery Therapeutics

Indication: Cancer

...Summary Licensing status Publication and contact information Cancer Cancer NDC80 homolog kinetochore complex component (NDC80); NIMA-related kinase...
BioCentury | Apr 23, 2009
Distillery Therapeutics

Indication: Neurology

...chain 1 (ITIH1); Inter-alpha trypsin inhibitor heavy chain 3 (ITIH3); guanine nucleotide binding protein-like-3 (GNL3); NIMA-related kinase...
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