BioCentury | Oct 12, 2017
Preclinical News

Team describes MECP2 gene therapy approach for Rett syndrome

In a paper published in Nature , researchers at the University of Edinburgh and colleagues showed that adeno-associated virus (AAV) delivery of a shortened version of the methyl CpG binding protein 2 ( MECP2 ; RTT) gene...
BioCentury | Jan 8, 2015
Distillery Therapeutics

Therapeutics: Nidogen-1 (NID1); NID2

...tetanus neurotoxin-induced paralysis during Clostridium tetani infection. In mouse motor neurons, full-length recombinant NID1 or NID2...
...loss of muscle function but an inactive mutant version of the peptide did not. In NID2...
...mice. Next steps include developing stable analogs of the nidogen peptides. TARGET/MARKER/PATHWAY: Nidogen-1 (NID1) ; NID2...
BioCentury | Jul 15, 2013
Regulation

Coding for utility

...growth factor (FGF) receptor 3 ( FGFR3 ; CD333 ), twist homolog 1 (TWIST1) and nidogen-2 (NID2)...
BioCentury | Jun 3, 2013
Company News

Predictive Biosciences diagnostic news

...growth factor (FGF) receptor 3 ( FGFR3 ; CD333 ), twist homolog 1 (TWIST1) and nidogen-2 (NID2)...
BioCentury | May 21, 2012
Company News

MDxHealth, Predictive Biosciences sales and marketing update

...and nidogen-2 (NID2) biomarkers. In 2010, MDxHealth granted Predictive exclusive, U.S. rights to the TWIST1 and NID2...
BioCentury | Jan 31, 2011
Clinical News

Bladder Cancer Assay diagnostic data

...and healthy controls showed that Predictive's CertNDx Bladder Cancer Assay using MMP2, FGFR3, TWIST1 and NID2...
...year, MDxHealth S.A. (Euronext:MDXH, Liege, Belgium) granted Predictive exclusive, U.S. rights to the TWIST1 and NID2...
...FGFR3) (CD333) Description: Non-invasive diagnostic urine test combining MMP2, FGFR3, twist homolog 1 (TWIST1) and nidogen-2 (NID2)...
BioCentury | Feb 22, 1999
Tools & Techniques

Inflection points

As news watchers come to realize, seemingly independent events have a way of piling up on themselves and pushing other topics into the background. With the stars thus aligned, it becomes impossible to ignore the...
BioCentury | Dec 14, 1998
Tools & Techniques

Diabetes Pipeline

Diabetes Pipeline Company Product Product type Therapeutic focus Status Ergo Science (ERGO) Ergoset bromocriptine dopamine D2 agonist Regulate glucose metabolism NDA nonapprovable Novo Nordisk NovoRapid short-acting insulin analog Regulate glucose metabolism NDA, MAA submitted SmithKline...
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