BioCentury | Aug 15, 2011
Product Development

Powering down cancer

...also can make NAD+ from external sources such as niacin. They do so by expressing nicotinate phosphoribosyltransferase (NAPRT1)...
...glioblastoma. Hobden said none of the tumor samples examined by the company have expressed the NAPRT1...
...kits. Similarly, Myrexis is looking to develop a diagnostic that could identify tumors lacking the NAPRT1...
BioCentury | Oct 4, 2010
Clinical News

Myrexis preclinical data

...In mice bearing nicotinate phosphoribosyltransferase ( NAPRT1 )-deficient pancreatic tumors, 75 mg/kg oral MPC-9528 on days 1...
...MPC-9528 alone was not achieved by co-administration of MPC-9528 and nicotinic acid in mice bearing NAPRT1-proficient...
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