07:00 , Jul 26, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Depression NADPH oxidase; neutrophil cytosolic factor 1 (NCF1; p47phox) In vitro and mouse studies suggest inhibiting NADPH...
07:00 , Jul 5, 2010 |  BioCentury  |  Emerging Company Profile

ProNoxis: Promoting ROS

It is widely accepted that reactive oxygen species promote tissue damage and inflammation in certain settings, but recent data suggest that reactive oxygen species may limit the inflammatory process in certain autoimmune diseases. On the...
08:00 , Dec 9, 2002 |  BC Week In Review  |  Company News

Arexis other research news

Researchers published in Nature Genetics the identification of Ncf-1, identified through positional cloning, as a protein capable of regulating arthritis severity in rats. Rats with the protective Ncf-1 allele showed reduced clinical scores in a...
08:00 , Dec 11, 1995 |  BC Week In Review  |  Clinical News

Progenitor cell gene therapy with the normal version of the p47phox gene data

SOMA and Baxter announced data from three of five patients in a Phase I trial, showing that two of the three had small numbers of granulocytes in the blood with fully restored function. Patients...