Free Trial Information
BioCentury | May 23, 2018
Distillery Techniques

Drug platforms

...the findings to design novel antagonists or agonists of NPY1R. DESCRIPTION: Crystal structure analysis of neuropeptide Y receptor...
...Beili Wu, Chinese Academy of Sciences, Shanghai, China email: beiliwu@simm.ac.cn Mark Zipkin Chinese Academy of Sciences Neuropeptide Y (NPY) Neuropeptide Y receptor...
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BioCentury | Mar 16, 2017
Targets & Mechanisms

Bone appétit!

...Melanocortin 4 receptor MOR (OPRM1) - μ opioid receptor NPY receptor - Neuropeptide Y receptor NPY5R - Neuropeptide Y receptor...
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BioCentury | Jan 9, 2014
Distillery Therapeutics

Indication: Endocrine/metabolic disease

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Neuropeptide Y receptor Y2 (NPY2R); peptide...
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BioCentury | Jul 11, 2013
Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Addiction Neuropeptide S receptor 1 (NPSR1; NPSR) Rat studies suggest the NPSR antagonist NCGC84 could help treat alcoholism. In rats, NCGC84 prevented alcohol-induced activation of...
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BioCentury | Jul 9, 2012
Strategy

Belviq breaks through

...Tables Targeting obesity Company Product Description Status Shionogi & Co. Ltd. (Tokyo:4507; Osaka:4507) Velneperit Oral neuropeptide Y receptor...
...type 4 (MC4R) partial agonist peptide Ph I (A) Shionogi & Co. Ltd. S-234462 Oral neuropeptide Y receptor...
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BioCentury | Apr 14, 2011
Distillery Therapeutics

Indication: Endocrine disease

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine disease Obesity Neuropeptide Y receptor Y2 (NPY2R); NPY4R...
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BioCentury | Feb 7, 2011
Product Development

Obesity Reset

...Serotonin (5-HT2C) receptor agonist Ph II Shionogi & Co. Ltd. (Tokyo:4507; Osaka:4507) Velneperit (S-2367) Oral neuropeptide Y receptor...
...OAP-189 (formerly TKS-1225) Oxyntomodulin analog Ph I Shionogi & Co. Ltd. (Tokyo:4507; Osaka:4507) S-234462 Oral neuropeptide Y receptor...
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BioCentury | Aug 12, 2010
Targets & Mechanisms

The GPCR-cancer connection

...cancer." In particular, Marshall noted that there are clinical antagonists available for some receptors, including neuropeptide Y receptor...
...Metabotropic glutamate receptor subtype 1 (mGluR1; GRM1) mGluR3 (GRM3) mGluR8 (GRM8) Melanocortin 3 receptor (MC3R) Neuropeptide Y receptor...
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BioCentury | May 3, 2010
Clinical News

7TM preclinical data

...model of chemotherapy-induced gastrointestinal disease, TM30339 improved survival and mucositis outcome post X-ray irradiation. The neuropeptide Y (NPY) receptor...
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BioCentury | Aug 31, 2009
Strategy

Neurogen chronicles

...Sees possible dose-limiting liver toxicity in a Phase I trial of NGD 95-1, a neuropeptide Y (NPY) receptor...
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