SNPs on 30 genomic loci could help predict the risk of schizophrenia. Genome-wide association studies in 47,559 schizophrenia patients and 70,936 healthy volunteers identified associations between the disease and SNPs on 30 loci, including...
Cell culture and goat studies suggest inhibiting miR-31 could help treat atrial fibrillation (AF). miR-31 levels were higher in atrial myocytes from AF patients and in the left ventricle of a goat model...
Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Inducible nitric oxide synthase 2 (NOS2; iNOS); epidermal growth factor receptor variant III (EGFRvIII) In...
The double-blind, U.S. Phase II Study 204 trial in 174 patients with moderate to severe acute migraine headache without aura showed that a single dose of oral 600 mg NXN-188 missed the primary endpoint of...
Technology: Neuronal nitric oxide synthase (nNOS) inhibitors
Disease focus: Neurology
Clinical status: Phase I
Founded: 2004 by Suman Rakhit, John Andrews and Shawn Maddaford
University collaborators: University of Arizona
Corporate partners: Undisclosed
Number of employees: 14
Funds raised: $48 million