01:12 , Aug 19, 2017 |  BioCentury  |  Product Development

Restoring dependence

Netris Pharma S.A.S. is aiming to boost rates and durations of responses to immunotherapies by targeting a population of slow-growing cells these therapies leave behind. The biotech’s mAbs restore the pro-apoptotic function of dependence receptors,...
00:55 , Mar 29, 2017 |  BC Week In Review  |  Clinical News

NP137: Ph I started

Netris began an open-label, 2-part, French Phase I trial to evaluate IV NP137 given every other week in about 44 patients. The dose-escalation part 1 will evaluate 1, 2, 4, 6, 9, 14 and 20...
07:00 , Aug 11, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Matrix metalloproteinase 9 (MMP9); netrin 1 (NTN1)

Ophthalmic disease INDICATION: Diabetic macular edema (DME) Patient sample and mouse studies suggest inhibiting MMP9 could help treat DME. Levels of MMP9 and a truncated form of the MMP9 substrate NTN1 were higher in vitreous humor samples...
07:00 , May 7, 2015 |  BC Innovations  |  Translation in Brief

NYU cuts to the bone with MRCT

New York University School of Medicine expects its recent deal with the not-for-profit MRC Technology will help the university extract more value from its therapeutic targets than if it had partnered them with a biotech...
07:00 , Jun 19, 2014 |  BC Innovations  |  Distillery Techniques

Technology: Markers

This week in techniques Approach Summary Licensing status Publication and contact information Markers Netrin 1 (NTN1) levels to predict invasive disease in medulloblastoma Studies in vitro and in...
07:00 , Mar 27, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Endocrine/metabolic disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity Netrin 1 (NTN1); unc-5 homolog B (UNC5B; UNC5H2) Human sample and mouse studies suggest...
08:00 , Jan 26, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Atherosclerosis Netrin 1 (NTN1) Studies in mice and in human samples...
07:00 , Apr 16, 2009 |  BC Innovations  |  Distillery Therapeutics

This week in therapeutics

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer ...
08:00 , Feb 19, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/ marker/pathway Summary Licensing status Publication and contact information Cancer ...