22:23 , Mar 23, 2018 |  BC Extra  |  Preclinical News

Paper reveals tissue-specificity of cancer growth genes

A study led by Harvard Medical School and Brigham and Women’s Hospital researchers published in Cell showed genes underlying cancer proliferation perform in a tissue-specific manner, potentially presenting a new development paradigm for targeted cancer...
07:00 , Oct 13, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Monocyte chemoattractant protein-1 (MCP-1; CCL2)

Cardiovascular disease INDICATION: Atherosclerosis Mouse studies suggest inhibiting MCP-1 in bone marrow stromal cells could help treat atherosclerosis. In a mouse model of atherosclerosis, MCP-1 knockout in cells expressing nestin (NES) - a marker for bone marrow...
08:00 , Nov 17, 2014 |  BioCentury  |  Emerging Company Profile

Swift western wind

Zephyrus Biosciences Inc. is developing its scWestern technology to perform Western blots on thousands of cells with single-cell resolution, which will enable researchers to study how protein concentrations vary within heterogeneous cell populations quickly and...
07:00 , Jul 24, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Adrenergic receptor b3 (ADRB3) Studies in patient samples and mice suggest protecting nestin-positive bone marrow mesenchymal...
07:00 , Mar 25, 2013 |  BC Week In Review  |  Company News

NsGene, StemCells deal

StemCells acquired from NsGene a patent family, including U.S. Patent Nos. 6,878,543 and 7,303,912 and European patent application 00973148. The patents claim cell cultures of glial fibrillary acidic protein (GFAP) and intermediate filament marker...
08:00 , Mar 21, 2005 |  BC Week In Review  |  Company News

Genzyme, ViaCell deal

GENZ will use VIAC's adult islet stem cells in preclinical diabetes studies. GENZ also will study methods of improving production of the cells. Financial terms were not disclosed. Separately, VIAC received an exclusive license to...
07:00 , Apr 30, 2001 |  BC Week In Review  |  Company News

NIH other research news

Researchers reported in Science the generation of cells that secrete insulin in the presence of glucose in a dose-responsive manner. The cells, derived from from an enriched population of nestin-positive cells derived from mouse embryoid...