BioCentury | Aug 25, 2016
Distillery Therapeutics

Therapeutics: WAS protein family member 3 (WASF3); NCK associated protein 1 (NCKAP1); cytoplasmic FMR1 interacting protein 1 (CYFIP1)

...Cancer INDICATION: Breast cancer Patient sample, cell culture and mouse studies suggest that inhibiting the WASF3-NCKAP1...
...two human breast cancer cell lines, shRNA targeting NCKAP1 or a stapled peptide inhibiting the NCKAP1-CYFIP1...
...the WASF3-NCKAP1-CYFIP1 complex in other metastatic cancers. TARGET/MARKER/PATHWAY: WAS protein family member 3 (WASF3) ; NCK associated protein 1 (NCKAP1)...
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