BioCentury | Feb 11, 2016
Distillery Therapeutics

Therapeutics: N-acylethanolamine acid amidase (NAAA; ASAHL)

...arthritis. In a rat model of arthritis, an NAAA inhibitor tool compound decreased levels of NAAA...
...Next steps could include testing NAAA inhibition in additional models of arthritis. TARGET/MARKER/PATHWAY: N-acylethanolamine acid amidase (NAAA; ASAHL...
BioCentury | Jul 29, 2010
Distillery Therapeutics

Indication: Inflammation

...a b-lactone-based inhibitor of NAAA that could help treat inflammation. In vitro, the compound inhibited NAAA...
...with the parent compound or vehicle control. More potent and stable analogs of the identified NAAA...
BioCentury | Apr 15, 2010
Strategy

Cisalpine translation

...hydrolase (FAAH) , which is a pain target, and N -acylsphingosine amidohydrolase-like ( ASAHL ; NAAA...
BioCentury | Dec 17, 2009
Distillery Therapeutics

Indication: Inflammation

...contact information Inflammation Inflammation N-Acylsphingosine amidohydrolase-like (ASAHL; NAAA) A study in mice suggests that inhibiting NAAA...
...A study in mice suggests that inhibiting NAAA could help treat inflammation. In mice, an NAAA...
...and motor deficits compared with saline control (p<0.05). Next steps include evaluating a pool of NAAA...
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