08:00 , Feb 11, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: N-acylethanolamine acid amidase (NAAA; ASAHL)

Autoimmune disease INDICATION: Arthritis Rat studies suggest inhibiting NAAA could help treat arthritis. In a rat model of arthritis, an NAAA inhibitor tool compound decreased levels of NAAA in the paw, paw edema, thermal hyperalgesia...
07:00 , Jul 29, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Inflammation

Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation N-Acylethanolamine acid amidase (NAAA; ASAHL) In vitro and mouse studies identified a b-lactone-based inhibitor of NAAA that could help treat inflammation. In vitro, the...
07:00 , Apr 15, 2010 |  BC Innovations  |  Strategy

Cisalpine translation

In Italy, a scarcity of local venture capital and biotechs has left academic researchers with few opportunities to commercialize their discoveries. A new drug discovery center at the Italian Institute of Technology hopes to change...
08:00 , Dec 17, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Inflammation

Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation N-Acylsphingosine amidohydrolase-like (ASAHL; NAAA) A study in mice suggests that inhibiting NAAA could help treat inflammation. In mice, an NAAA inhibitor decreased spinal cord...