19:09 , Jan 18, 2017 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Neurology Mouse studies suggest inhibiting NAT8L could help treat Canavan disease. In a mouse model of the disease, knockout of NAT8L decreased vacuolation of the cerebellum, swelling of Purkinje cell axons and apoptosis in...
08:00 , Feb 9, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) N-Acetyltransferase 8 (NAT8); NAT8B Human brain tissue and cell culture studies suggest NAT8 and NAT8B could be antagonized to treat AD. In...
07:00 , Apr 29, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Renal disease

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Renal disease Renal disease N-acetyltransferase 8 GCN5-related putative (NAT8); solute carrier family 7 cationic amino acid transporter y+ system member 9 (SLC7A9) A genomewide study...