03:00 , Aug 10, 2018 |  BC Innovations  |  Targets & Mechanisms

Getting to function

A new target for sarcopenia that increases muscle function directly, in addition to adding muscle mass, could help address calls from patients and regulators to make functional recovery central to drug development in the indication. Sarcopenia...
16:35 , Aug 3, 2018 |  BC Week In Review  |  Clinical News

Acceleron's ACE-083 increases muscle volume in Phase II for Charcot-Marie-Tooth disease

Acceleron Pharma Inc. (NASDAQ:XLRN) reported preliminary data from 18 patients with Charcot-Marie-Tooth disease in Part 1 of a Phase II trial showing that ACE-083 increased mean total muscle volume by 12.6-14.2%, increased mean contractile muscle...
20:06 , Aug 1, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Lung cancer Patient sample, cell culture and mouse studies suggest inhibiting activin signaling could enhance the efficacy of platinum-based chemotherapy in KRAS-mutant lung cancer. In 59 patients with stage IV non-small cell lung cancer (NSCLC)...
18:11 , Jul 27, 2018 |  BC Week In Review  |  Company News

Biogen acquires neuromuscular assets from AliveGen

Biogen Inc. (NASDAQ:BIIB) said it acquired two early stage neuromuscular assets from AliveGen USA Inc. (Thousand Oaks, Calif.) and reported rising U.S. sales of spinal muscular atrophy (SMA) therapy Spinraza nusinersen in its 2Q18 earnings...
17:58 , Jul 24, 2018 |  BC Extra  |  Company News

Biogen acquires neuromuscular assets, reports 2Q earnings

Biogen Inc. (NASDAQ:BIIB) said it acquired two early stage neuromuscular assets from AliveGen USA Inc. (Thousand Oaks, Calif.) and reported rising U.S. sales of spinal muscular atrophy (SMA) therapy Spinraza nusinersen in its 2Q18 earnings...
19:26 , Jun 1, 2018 |  BC Week In Review  |  Financial News

Scholar Rock raises $75M IPO

Scholar Rock Holding Corp. (NASDAQ:SRRK) raised $75 million on May 23 through the sale of 5.4 million shares at $14 in an IPO. Jefferies, Cowen, BMO Capital Markets and Wedbush PacGrow underwrote the deal. Scholar Rock...
04:18 , May 24, 2018 |  BC Extra  |  Financial News

Scholar Rock shares rise after IPO

Scholar Rock Holding Corp. (NASDAQ:SRRK) gained $1.50 (11%) to $15.50 in its first day of trading Thursday after raising $75 million through the sale of 5.4 million shares at $14 in an IPO. Jefferies, Cowen,...
15:24 , May 4, 2018 |  BC Week In Review  |  Financial News

Scholar Rock files for IPO

Scholar Rock Holding Corp. (Cambridge, Mass.) proposed on April 27 to raise up to $75 million in an IPO on NASDAQ underwritten by Jefferies, Cowen, BMO Capital Markets and Wedbush PacGrow. Scholar Rock is developing a...
21:39 , Apr 28, 2018 |  BC Extra  |  Financial News

Scholar Rock files for IPO

Scholar Rock Holding Corp. (Cambridge, Mass.) proposed to raise up to $75 million in an IPO on NASDAQ underwritten by Jefferies, Cowen, BMO Capital Markets and Wedbush PacGrow. Scholar Rock is developing a pipeline of candidates...
22:30 , Feb 2, 2018 |  BioCentury  |  Product Development

AA Viral meme

Gene therapy pioneer James Wilson’s revelation of two new types of toxicity in animals receiving high systemic doses of adeno-associated viral vectors is unlikely to herald a major disruption of the AAV space, though it...