BioCentury | Apr 10, 2019
Distillery Therapeutics

Inhibiting a MYLK splice variant for IBD and colitis

...Inflammatory bowel disease (IBD); colitis Cell culture and mouse studies identified an inhibitor of an MYLK...
...compound library for binding to immunoglobulin-cell adhesion molecule 3 (IgCAM3), an extra domain in the MYLK...
...Crohn's disease or other intestinal diseases associated with loss of barrier function. TARGET/MARKER/PATHWAY: Myosin light chain kinase (MYLK; MLCK...
BioCentury | Nov 25, 2013
Clinical News

Neuroptis preclinical data

...Phase I/II testing with the eye drop formulation of ML7, a myosin light chain kinase ( MYLK ; MLCK...
BioCentury | Nov 11, 2010
Distillery Therapeutics

Indication: Infectious disease

...9 (MYH9); myosin light chain kinase (MYLK; MLCK) Cell culture and mouse studies suggest that inhibiting MYH9 or MYLK...
...shRNA. In cell culture and a mouse model of HSV-1 stromal keratitis, an inhibitor of MYLK...
BioCentury | Apr 23, 2007
Tools & Techniques

Ranking the kinase kingdom

...contributing to its role as a cancer gene. But such mutations also were found in MLCK...
BioCentury | May 5, 2003
Company News

Northwestern University other research news

...and showed enhanced survival during subsequent mechanical ventilation (p=0.001). The researchers also discovered a myosin light chain kinase (MLCK...
...controls in the same model of ALI. Northwestern University , Chicago, Ill., et al. Product: Myosin light chain kinase...
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