17:35 , May 25, 2017 |  BC Innovations  |  Emerging Company Profile

Total reprogramming

University of Cambridge spinout Elpis Biomed Ltd. has a platform that rapidly produces stockpiles of pure, mature cell types from human pluripotent stem cells. While the company is first focusing on creating well-defined disease models,...
14:16 , Apr 18, 2017 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Cell models A method for differentiating hPSCs into specific cell types by expressing select transcription factors could aid the development of cell-based disease models. The method involved engineering hPSCs via CRISPR-associated protein 9 (Cas9)-guided genomic...
07:00 , Oct 21, 2010 |  BC Innovations  |  Tools & Techniques

ModeRNA approach to iPS cells

A Boston-based team has used synthetic, modified mRNAs to revert somatic cells to pluripotency, thus taking retroviral vectors out of the reprogramming equation.1As an added bonus, the modified-mRNA protocol worked in about half the time...
07:00 , Oct 14, 2010 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Modified mRNAs to generate induced pluripotent stem (iPS) cells In vitro experiments suggest that...