17:35 , May 25, 2017 |  BC Innovations  |  Emerging Company Profile

Total reprogramming

University of Cambridge spinout Elpis Biomed Ltd. has a platform that rapidly produces stockpiles of pure, mature cell types from human pluripotent stem cells. While the company is first focusing on creating well-defined disease models,...
14:16 , Apr 18, 2017 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Cell models A method for differentiating hPSCs into specific cell types by expressing select transcription factors could aid the development of cell-based disease models. The method involved engineering hPSCs via CRISPR-associated protein 9 (Cas9)-guided...
07:00 , Oct 21, 2010 |  BC Innovations  |  Tools & Techniques

ModeRNA approach to iPS cells

A Boston-based team has used synthetic, modified mRNAs to revert somatic cells to pluripotency, thus taking retroviral vectors out of the reprogramming equation. 1 As an added bonus, the modified-mRNA protocol worked in about half...
07:00 , Oct 14, 2010 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Modified mRNAs to generate induced pluripotent stem (iPS) cells In vitro experiments suggest that synthetic, modified mRNAs could be used to...