18:25 , Jun 13, 2018 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Cell models A method of directly reprogramming human adult T cells into neurons could be used to generate cell-based models of neurological diseases. The method involves transfecting primary human T cells with a combination...
07:00 , May 26, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: Baculovirus-based vector system for transient, simultaneous expression of multiple genes for genome editing or cellular reprogramming

Drug platforms TECHNOLOGY: Expression systems A baculoviral vector-based system for transient gene expression could be used to develop genome editing- or cellular reprogramming-based therapies. The vector system involved modifying baculovirus by inserting a plasmid containing...
07:00 , Aug 18, 2011 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Direct conversion of fibroblasts into functional neurons A method for directly converting human fibroblasts into functional neurons could be useful for...
08:00 , Feb 18, 2010 |  BC Innovations  |  Distillery Techniques

Technology: Approach

Approach Summary Licensing status Publication and contact information Drug platforms Direct conversion of fibroblasts into functional neurons A cell culture study suggests that the direct conversion of mouse fibroblasts into functional neurons could be useful...
08:00 , Feb 18, 2010 |  BC Innovations  |  Tools & Techniques

Bypassing the iPS logjam

Researchers at the Stanford University School of Medicine have found a way to efficiently convert mouse fibroblasts into functional neurons without first reverting the skin cells to a pluripotent state. 1 The protocol could make...