07:00 , Oct 1, 2009 |  BC Innovations  |  Cover Story

Targeting the TB proteasome

Researchers at Weill Cornell Medical College have identified compounds that can kill non-replicating Mycobacterium by selectively and irreversibly inhibiting the organism's proteasome. 1 Beyond the potential for new therapeutics for tuberculosis, the findings provide a...
07:00 , Sep 24, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Tuberculosis (TB) Mycobacterium tuberculosis proteasome A study in cell culture identified oxathiazol-2-one M. tuberculosis proteasome inhibitors that could help treat TB. Dialysis and kinetics...