BC Innovations | Jul 25, 2013
Distillery Therapeutics

Indication: Infectious disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Tuberculosis Mycobacterium tuberculosis decaprenylphosphoryl-b-d-ribose 2ʹ-oxidase (dprE1); M. tuberculosis molybdopterin biosynthesis protein (moeW) Mouse and cell culture studies suggest an inhibitor of dprE1 and moeW...
BC Innovations | Jul 11, 2013
Targets & Mechanisms

Targeting TB persistence

A group of researchers from California and New York has identified a small molecule with activity against currently intractable nonreplicating stages and drug-resistant strains of Mycobacterium tuberculosis . 1 The compound, which works by blocking a...
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