BioCentury | Dec 20, 2012
Strategy

MRC Technology extends reach

...agonists for ischemia/reperfusion injury Hit to lead William Harvey Research Institute Mycobacterium tuberculosis glucanase GlgE (glgE) Inhibitors of glgE...
BioCentury | Apr 8, 2010
Distillery Therapeutics

Indication: Infectious disease

...glgE could help treat TB. In cultured as compared with wild-type M. tuberculosis, inactivation of glgE...
...1-phosphate and bacterial death. In a mouse model of M. tuberculosis infection, bacteria with inactive glgE...
...and spleen compared with wild-type bacteria. Next steps include screening for small molecule inhibitors of glgE...
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