16:41 , Jun 5, 2017 |  BC Extra  |  Clinical News

Zika virus hijacks neurodevelopmental protein to replicate

In a paper published in Science, University of Cambridge researchers show the Zika virus hijacks neurodevelopmental protein Musashi RNA-binding protein 1 (MSI1) in neural stem cells, increasing viral replication and preventing neural stem cell function....
07:00 , Jun 23, 2016 |  BC Innovations  |  Translation in Brief

Musashi's dual duel

The Musashi genes were originally named for the samurai who fought with two swords because, when discovered in flies, their mutation created double-shafted bristles. Now, a pair of studies double down on the name, showing...
07:00 , Mar 20, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colon cancer Notch 3 (NOTCH3); Musashi RNA binding protein 1 (MSI1) In vitro and mouse studies suggest...
07:00 , Aug 19, 2010 |  BC Innovations  |  Targets & Mechanisms

Leukemia takes it up a NOTCH

The Notch pathway has been linked to aggressive growth in a range of tumor types but had not previously been considered a prime target for myeloid leukemia therapies. Separate American teams now have identified two...