BioCentury | Oct 29, 2015
Product R&D

Qureing antibiotic resistance

...Infectious Diseases (NIAID) grants since 2011 to validate its targets. Spero Therapeutics LLC is developing MvfR...
...to access the site of infection. In 2014, Roche obtained the option to acquire an MvfR...
...Umeå, Sweden Washington University in St Louis, St. Louis, Mo. Targets and Compounds MvfR - Multiple virulence factor regulator...
BioCentury | Aug 14, 2015
Top Story

Roche acquiring GeneWeave

...treat multi-drug resistant Gram-negative bacteria and obtained an exclusive option to acquire a multiple virulence factor regulator ( MvfR...
BioCentury | Jun 15, 2015
Finance

Spero's Finnish-ing touch

...Spero also plans to use a portion of the funding to advance an inhibitor of multiple virulence factor regulator (MvfR)...
...OTCQX:RHHBY) has an exclusive option to acquire the program at the time of the submission. MvfR...
BioCentury | Jun 9, 2015
Financial News

Spero raises $30M, expands antibiotic portfolio

...has an exclusive option to acquire a preclinical program from Spero that inhibits multiple virulence factor regulator ( MvfR...
BioCentury | Feb 5, 2015
Company News

The Medicines Co. acquires Annovation

...option to acquire a preclinical program from Spero Therapeutics LLC (Cambridge, Mass.) inhibiting multiple virulence factor regulator ( MvfR...
BioCentury | Oct 6, 2014
Finance

Atlas' next chapter

...program. Meanwhile, Roche has an exclusive option to acquire a preclinical program from Spero inhibiting multiple virulence factor regulator (MvfR)...
...the time of an IND filing. Spero also plans to start anti-infective programs to complement MvfR...
BioCentury | Sep 25, 2014
Distillery Therapeutics

Indication: Infectious disease

...of MvfR that could help treat Pseudomonas aeruginosa infection. In P. aeruginosa culture, the lead MvfR...
...mouse models of burn wound or lung P. aeruginosa infection, i.v. injection of the lead MvfR...
...increased survival compared with vehicle control injection. Next steps include studying the broad applicability of MvfR...
BioCentury | Jul 28, 2014
Emerging Company Profile

Spero: Killing the quiet

...LLC hopes to neutralize these bacteria and increase their sensitivity to bactericidal compounds by inhibiting MvfR...
...formation are regulated by conserved master transcriptional regulators including Pseudomonas MvfR (multi virulence factor regulator). "MvfR...
...is also a venture partner at Atlas Venture . Spero has exclusively licensed inhibitors of MvfR...
BioCentury | Apr 14, 2014
Company News

Spero Therapeutics, Roche deal

...website for Rahme's lab, she is developing anti-infectives that include selective inhibitors of the MvfR (multiple virulence factor regulator)-dependent...
BioCentury | Apr 10, 2014
Company News

Spero, Roche in infectious disease deal

...website for Rahme's lab, she is developing anti-infectives that include selective inhibitors of the MvfR (multiple virulence factor regulator)-dependent...
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