07:00 , Apr 14, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Histone methyltransferase DOT1L (DOT1L); bromodomain containing 4 (BRD4)

Cancer INDICATION: Leukemia Cell culture studies suggest combining inhibitors of DOT1L and BRD4 could help treat mixed lineage leukemia (MLL). In mouse hematopoietic cells transformed by a chimeric version of the MLL-ENL fusion oncogene ,...
07:00 , Apr 16, 2009 |  BC Innovations  |  Distillery Techniques

Technology: Disease models

This week in techniques Approach Summary Licensing status Publication and contact information Disease models Mouse models of acute myelogenous leukemia (AML) for predicting chemotherapy response A series of mouse models of human AML could be...