BioCentury | May 31, 2017
Distillery Therapeutics

Cancer

...INDICATION: Colorectal cancer Cell culture and mouse studies identified a JAG2 -targeting MT-TL1 fragment that could...
...colorectal cancer. The fragment consisted of a dicer 1 ribonuclease type III (DICER1)-cleaved form of MT-TL1...
...steps could include testing the fragment in additional colorectal cancer models. TARGET/MARKER/PATHWAY: Jagged 2 (JAG2); mitochondrially encoded tRNA leucine 1 (UUA/G) (MT-TL1)...
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