BC Innovations | Apr 28, 2016
Distillery Therapeutics

Therapeutics: Microtubule-associated protein 1 light chain 3 β (MAP1LC3B; LC3B)

Cancer INDICATION: Cancer; prostate cancer In vitro, cell culture and mouse studies identified a benzo[a]quinolizidine-based agonist of MAP1LC3B that could help treat prostate cancer. Chemical synthesis and in vitro testing of benzo[a]quinolizidine analogs identified a...
BC Innovations | Nov 4, 2010
Distillery Therapeutics

Indication: Pulmonary disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Emphysema Microtubule-associated protein 1 light chain 3b (MAP1LC3B; LC3B) In vitro and mouse studies suggest that inhibiting LC3B could help...
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