17:50 , May 16, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Alzheimer’s disease (AD)...
13:20 , May 9, 2017 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Huntington’s disease (HD)...
22:00 , Apr 4, 2017 |  BC Innovations  |  Distillery Techniques

Assays and screens; other

TECHNOLOGY: Bioinformatics screens; computational models A computational tool combining data on tumor genome sequences, protein-protein interactions, and gene-dose effects on those interactions could help identify therapeutic pathways and targets for cancer. For a selected cancer...
07:00 , Apr 7, 2011 |  BC Innovations  |  Targets & Mechanisms

Pancreatic cancer: stressed to death

U.S. and EU researchers have shown that the generic malaria drug chloroquine can treat pancreatic cancer by inhibiting autophagy, 1 a process by which cells degrade their own cytosolic components to prolong cell survival. The...
07:00 , Sep 30, 2010 |  BC Innovations  |  Targets & Mechanisms

Building up degradation

A trio of papers makes a case for purging neurotoxic misfolded proteins from neurons by stimulating two protein degradation processes: autophagy and proteasome-based proteolysis. 1-3...