19:58 , Sep 26, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Brain cancer; breast cancer; colorectal cancer Patient sample and mouse studies suggest dual inhibition of miR-25 and miR-93 or promoting cGAS expression could help treat brain, breast and colorectal cancers. In patients, high brain...
07:00 , Apr 16, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: MicroRNA-93 (miR-93); DNA-directed DNA polymerase η (POLH)

Cancer INDICATION: Ovarian cancer Studies in cell culture, mice and patient samples suggest miR-93 mimetics or POLH inhibitors could help treat ovarian cancer. In samples from ovarian cancer patients and ovarian cancer cell lines, levels...
07:00 , Sep 12, 2013 |  BC Innovations  |  Tools & Techniques

Molecular biocontainment for the flu

A team from the Icahn School of Medicine at Mount Sinai and the University of Maryland, College Park has engineered a flu virus that is transmissible among ferrets but not humans. 1 The microRNA-based containment...