BioCentury | May 12, 2016
Distillery Therapeutics

Therapeutics: MicroRNA-551b (miR-551b); signal transducer and activator of transcription 3 (STAT3)

...Cancer INDICATION: Ovarian cancer Patient sample, cell culture and mouse studies suggest inhibiting miR-551b or STAT3...
...or STAT3 could help treat serous ovarian cancer. In patients with high-grade serous ovarian cancer, miR-551b...
...with poor survival. In two human ovarian cancer cell lines overexpressing miR-551b, an oligonucleotide targeting miR-551b...
BioCentury | Feb 19, 2015
Distillery Therapeutics

Therapeutics: Creatine kinase brain (CKB); microRNA-483-5p (miR-483-5p); microRNA-551a (miR-551a)

Cancer INDICATION: Colorectal cancer Mouse studies suggest upregulating miR-483-5p and miR-551a or inhibiting CKB could help treat and prevent liver metastasis in colon cancer. In mouse xenograft models of metastatic colon cancer, overexpression of miR-483-5p...
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