BioCentury | May 12, 2016
Distillery Therapeutics

Therapeutics: MicroRNA-551b (miR-551b); signal transducer and activator of transcription 3 (STAT3)

Cancer INDICATION: Ovarian cancer Patient sample, cell culture and mouse studies suggest inhibiting miR-551b or STAT3 could help treat serous ovarian cancer. In patients with high-grade serous ovarian cancer, miR-551b levels were higher in ovarian...
BioCentury | Feb 19, 2015
Distillery Therapeutics

Therapeutics: Creatine kinase brain (CKB); microRNA-483-5p (miR-483-5p); microRNA-551a (miR-551a)

...Cancer INDICATION: Colorectal cancer Mouse studies suggest upregulating miR-483-5p and miR-551a or inhibiting CKB could help...
...in colon cancer. In mouse xenograft models of metastatic colon cancer, overexpression of miR-483-5p or miR-551a...
...for colorectal cancer and undisclosed solid tumors. TARGET/MARKER/PATHWAY: Creatine kinase brain (CKB) ; microRNA-483-5p (miR-483-5p); microRNA-551a (miR-551a)...
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