BioCentury | May 23, 2018
Distillery Techniques

Assays and screens; biomarkers

...from pancreatic cancer patients and healthy volunteers, the method identified 12 miRNAs -- including miR-122, miR-483-5p...
...doi:10.1158/0008-5472.CAN-17-3703 CONTACT: David Issadore, University of Pennsylvania, Philadelphia, Pa. email: daveissadore@gmail.com Sandi Wong University of Pennsylvania MicroRNA-122 (miR-122) MicroRNA-186-5p (miR-186-5p) MicroRNA-483-5p (miR-483-5p) Cancer...
BioCentury | Feb 19, 2015
Distillery Therapeutics

Therapeutics: Creatine kinase brain (CKB); microRNA-483-5p (miR-483-5p); microRNA-551a (miR-551a)

...Cancer INDICATION: Colorectal cancer Mouse studies suggest upregulating miR-483-5p and miR-551a or inhibiting CKB could help...
...liver metastasis in colon cancer. In mouse xenograft models of metastatic colon cancer, overexpression of miR-483-5p...
...preclinical development for colorectal cancer and undisclosed solid tumors. TARGET/MARKER/PATHWAY: Creatine kinase brain (CKB) ; microRNA-483-5p (miR-483-5p)...
BioCentury | Jun 26, 2014
Distillery Techniques

Technology: Drug delivery

Approach Summary Licensing status Publication and contact information Drug delivery Ex vivo GI organoids to model cancer progression and evaluate driver genes Ex vivo and mouse studies suggest GI organoid cultures could help model colorectal...
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