BioCentury | Jun 7, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: May 2018

...sample, cell culture and mouse studies suggest promoting expression of the miR-371-373 cluster encoding miR-372, miR-371...
BioCentury | May 30, 2018
Distillery Therapeutics

Cancer

...Patient sample, cell culture and mouse studies suggest promoting expression of the miR-371-373 cluster encoding miR-371...
...tumorsphere formation compared with a non-specific shRNA. Also in the cell line, overexpression of the miR-371-373...
...miR-371-373 cluster. In three xenograft mouse models of metastatic colorectal cancer, tumor-specific overexpression of the miR-371-373...
BioCentury | Sep 1, 2016
Distillery Therapeutics

Therapeutics: Peroxiredoxin 6 (PRDX6); microRNA 371-3p (miR-371-3p)

...Cancer INDICATION: Lung cancer Patient sample, cell culture and mouse studies suggest promoting expression of miR-371-3p...
...expression of PRDX6 correlated with poor survival. In a Tarceva-treated human lung cancer cell line, miR-371-3p...
...relapsing animals compared with unmodified pre-miR-371-3p expression. Next steps could include testing PRDX6 inhibition and miR-371-3p...
BioCentury | Nov 18, 2010
Distillery Therapeutics

Indication: Cancer

...Summary Licensing status Publication and contact information Cancer Liver cancer MicroRNA-100 (miR-100); miRNA-let7a-2 (MIRLET7a2; LET-7a2); miR-371...
...help guide treatment for liver cancer. Expression profiling in hepatoblastoma tumors identified four miRNAs-miR-100, LET-7a2, miR-371...
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