BC Innovations | Jun 7, 2017
Distillery Therapeutics

Infectious disease

INDICATION: Viral infection Mouse studies suggest miR-31 inhibitors could help treat chronic lymphocytic choriomeningitis virus (LCMV) infection. In a mouse model of chronic LCMV infection, T cell-specific knockout of miR-31 decreased disease scores and serum...
BC Innovations | Jun 9, 2016
Distillery Therapeutics

Therapeutics: MicroRNA-31 (miR-31); neuronal nitric oxide synthase 1 (NOS1; nNOS)

Cardiovascular disease INDICATION: Fibrillation Cell culture and goat studies suggest inhibiting miR-31 could help treat atrial fibrillation (AF). miR-31 levels were higher in atrial myocytes from AF patients and in the left ventricle of a...
BC Innovations | Mar 31, 2011
Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer MicroRNA-31 (miR-31) Mouse studies suggest that miR-31 could help treat cancer metastasis. In mice with metastatic breast cancer, inducing miR-31...
BC Innovations | Mar 18, 2010
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lung cancer MicroRNA-31 (miR-31); LATS large tumor suppressor homolog 2 (LATS2); protein phosphatase 2 regulatory subunit B a-isoform (PPP2R2A); protein phosphatase 2 (PPP2CA; PP2A) Studies...
BC Innovations | Jul 9, 2009
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer MicroRNA-31 (miRNA-31) Studies in cell culture and in mice suggest that enhancing miRNA-31 levels in breast cancer tumors could help prevent metastasis. In...
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