BioCentury | Aug 29, 2018
Distillery Therapeutics

Musculoskeletal

...inhibiting miR-23b and miR-218 could help treat DM1. In myoblast cells from a DM1 patient, miR-23b...
...include identifying and testing additional miR-23b and miR-218 inhibitors in models of DM1. TARGET/MARKER/PATHWAY: MicroRNA-23b (miR-23b...
...email: Mbeatriz.Llamusi@uv.es CONTACT: Ruben Artero, same affiliation as above email: ruben.artero@uv.es Alicia Parker University of Valencia MicroRNA-218 (miR-218) MicroRNA-23b (miR-23b) Myotonic...
BioCentury | Nov 8, 2012
Distillery Therapeutics

Indication: Cancer

...and mouse studies suggest increasing miR-23b signaling could help treat prostate cancer. In patient samples, miR-23b...
...hyperplasia and normal tissue. In a mouse xenograft model of prostate cancer, intratumoral delivery of miR-23b...
...with delivery of control miRNA. Next steps could include evaluating vehicles for targeted delivery of miR-23b...
BioCentury | Jun 14, 2012
Distillery Therapeutics

Indication: Autoimmune disease

...rheumatoid arthritis (RA); multiple sclerosis (MS) MicroRNA-23b (miR-23b) Patient sample and mouse studies suggest agonizing miR-23b...
...inflammatory genes and disease progression compared with normal miR-23b expression. Next steps include developing a miR-23b...
BioCentury | May 19, 2011
Distillery Therapeutics

Indication: Ophthalmic disease

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Age-related macular degeneration (AMD) MicroRNA-23 (miR-23); miR-27 Mouse studies suggest inhibiting miR-23 or miR-27 could help treat AMD and other...
BioCentury | Feb 26, 2009
Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/ marker/ pathway Summary Licensing status Publication and contact information Cancer Cancer c-Myc (MYC); microRNA-23a (miRNA-23a); miRNA-23b Studies in cell culture suggest that increasing miRNA-23a and miRNA-23b activity could be...
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