BioCentury | Mar 24, 2016
Distillery Therapeutics

Therapeutics: MicroRNA-219 (miR-219)

...Neurology INDICATION: Schizophrenia Patient sample and cell culture studies suggest inhibiting miR-219 could help treat schizophrenia...
...help treat schizophrenia, which has been associated with low neural stem cell proliferation. Levels of miR-219...
...virus. Next steps could include testing inhibition of miR-219 in animal models of schizophrenia. TARGET/MARKER/PATHWAY: MicroRNA-219 (miR-219)...
BioCentury | Dec 5, 2013
Distillery Therapeutics

Indication: Cancer

...information Cancer Bone metastases MicroRNA-141 (miR-141); miR-219 Cell culture and mouse studies suggest miR-141 and miR-219...
...medium from weakly metastatic tumors did not. miRNA profiling identified 5 miRNAs, including miR-141 and miR-219...
...medium-induced differentiation compared with normal expression. In mouse xenograft models of bone metastasis, miR-141 and miR-219...
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