07:00 , Oct 27, 2016 |  BC Innovations  |  Distillery Therapeutics

Biomarkers

TECHNOLOGY: Gene profiling A panel of five microRNAs could be used for the differential diagnosis of subtypes of aggressive prostate cancer and to predict the risk of disease progression. Exon sequencing of serum samples from...
07:00 , Aug 11, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: MicroRNA-9 (miR-9); miR-200c

Cancer INDICATION: Breast cancer Patient sample and mouse studies suggest inhibiting miR-9 or promoting miR-200c expression could help treat triple-negative breast cancer (TNBC). In patient samples, high tumor miR-9 levels correlated with poor metastasis-free survival...
08:00 , Dec 12, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Transcription activator-like effector nucleases (TALENs) selectively targeting individual microRNAs A library of TALEN-mediated miRNA knockouts could help study miRNA function. A...
07:00 , Aug 27, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact nformation Cancer Breast cancer BMI1 polycomb ring finger oncogene (BMI1); microRNA-200c (miRNA-200c) Studies in mice and in cell culture suggest that increasing miRNA-200c expression in breast tissue...