BC Innovations | Apr 5, 2019
Tools & Techniques

Second shot for shRNA

Having long been demoted to tool compound status, shRNA is gaining renewed attention as a therapeutic modality by offering a simpler path to creating next-generation cell therapies than gene editing. Celyad has jumped in, using...
BC Innovations | Aug 20, 2015
Distillery Therapeutics

Therapeutics: MicroRNA-196a (miR-196a); v-myc myelocytomatosis viral oncogene homolog (MYC; c-Myc); homeobox B7 (HOXB7)

Cancer INDICATION: Breast cancer Studies in patient samples, cell culture and mice suggest miR-196a or inhibition of MYC could help treat tamoxifen-resistant breast cancer. In tumors from estrogen receptor-positive breast cancer patients previously treated with...
BC Innovations | Aug 8, 2013
Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Huntington's disease (HD) Huntingtin (HTT); microRNA-196a (miR-196a) Mouse and cell culture studies suggest miR-196a could help treat HD. In a mouse model for HD, miR-196a...
BC Innovations | Jun 28, 2012
Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Spinal and bulbar muscular atrophy (SBMA) MicroRNA-196a (miR-196a) Studies in cell culture and in mice suggest viral delivery of miR-196a could...
BC Innovations | Feb 16, 2012
Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Gastrointestinal cancer MicroRNA-196a (miR-196a); HOX transcript antisense RNA (HOTAIR) Patient sample and cell culture studies suggest miR-196a or HOTAIR could be...
BioCentury | Jun 1, 2009
Emerging Company Profile

Asuragen: Cutting pancreatic surgeries

Patients with pancreatic cancer and pancreatitis present with similar symptoms, and are often given ultrasound tests to confirm the presence or absence of lesions. About 15% of these tests are inconclusive, and as a result...
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