18:43 , Oct 18, 2018 |  BC Innovations  |  Distillery Therapeutics

Musculoskeletal; autoimmune disease

INDICATION: Osteoporosis; arthritis Mouse studies suggest inhibiting miR-182 could help treat osteoporosis and arthritis. In a mouse model of estrogen deficiency-induced osteoporosis, myeloid lineage osteoclast precursor-specific knockout of miR-182 or chitosan nanoparticles loaded with an...
23:41 , Jun 15, 2017 |  BC Innovations  |  Translation in Brief

MicroRNA's big role in pain

In Science this month, Karolinska Institute researchers uncovered the mechanism of a microRNA complex in pain and showed it functions in a neuronal population not currently targeted by any therapeutics. The authors believe the neurons...
17:37 , Jan 25, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Breast cancer; lung cancer Patient sample and cell culture studies suggest inhibiting miR-182 could help treat metastatic breast and lung cancers. In patient, levels of miR-182 were higher in tumors than in matched normal...
07:00 , Oct 20, 2016 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Breast cancer Cell and mouse studies suggest miR-96 or miR-182 could help treat metastatic breast cancer. In human and mouse breast cancer cell lines, a plasmid encoding miR-96 or miR-182 decreased migration and invasiveness...