20:08 , Jun 19, 2019 |  BC Innovations  |  Distillery Therapeutics

Inhibiting miR-181a and miR-181b could treat obesity

DISEASE CATEGORY: Endocrine/metabolic INDICATION: Obesity Inhibition of miR-181a and miR-181b or treatment with indole -- a negative regulator of the two microRNAs -- could help treat obesity. Expression of miR-181a2 and miR-181b2 in white adipose...
07:00 , Jun 7, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Inflammation

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation MicroRNA-181b (miR-181b) Patient sample and mouse studies suggest agonizing miR-181b could help treat inflammation. In a mouse model of endotoxic...
08:00 , Nov 10, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer MicroRNA-222 (miR-222); miR-181b Studies in mice suggest inhibiting miR-222 or miR-181b could help treat tamoxifen-resistant breast cancer. In tamoxifen-treated xenograft mice with drug-resistant...
07:00 , May 6, 2010 |  BC Innovations  |  Distillery Techniques

Technology: Assays & screens

Approach Summary Licensing status Publication and contact information Assays & screens MicroRNA-based scoring system to predict outcomes in patients with chronic lymphoblastic leukemia (CLL) An miRNA-based scoring system could help predict outcomes in CLL patients....