07:00 , Jun 30, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: MicroRNA-150 (miR-150); FMS-like tyrosine kinase 3 (FLT3; CD135); FMS-like tyrosine kinase 3 ligand (FLT3LG)

Cancer INDICATION: Acute myelogenous leukemia (AML); leukemia Patient sample, cell culture and mouse studies suggest miR-150, a negative regulator of FLT3, could help treat FLT3-driven AML and mixed lineage leukemia (MLL). miR-150 levels were lower in blood...
07:00 , Oct 8, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: MicroRNA-150 (miR-150)

Ophthalmic disease INDICATION: Ophthalmic disease Cell culture and mouse studies suggest miR-150 could help treat retinopathy and other ophthalmic diseases involving pathologic neovascularization. miR-150 levels were lower in the retinas and new retinal blood vessels in a...
08:00 , Dec 12, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug delivery

This week in techniques Approach Summary Licensing status Publication and contact information Drug delivery Short RNA delivery by engineered B cells A study in cell culture and mice...
08:00 , Dec 12, 2013 |  BC Innovations  |  Tools & Techniques

Plan B for anti-miRNA

Formulating and delivering therapeutic anti-microRNAs has been a big challenge in the burgeoning anti-miRNA space. Now, a University of California team has proof of concept for a surprisingly simple way to deliver these molecules into...