07:00 , Jun 30, 2016 |  BC Innovations  |  Distillery Techniques

Techniques: A 15-microRNA (miRNA) signature to predict survival in patients with colon, pancreatic and stomach cancers

Biomarkers TECHNOLOGY: Gene profiling A 15-microRNA signature associated with high doublecortin-like kinase 1 (DCLK1) activity could help predict survival in colon, pancreatic and stomach cancers. In colon, esophageal, pancreatic, rectal and stomach tumor samples from...
08:00 , Dec 12, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Transcription activator-like effector nucleases (TALENs) selectively targeting individual microRNAs A library of TALEN-mediated miRNA knockouts could help study miRNA function. A...
08:00 , Dec 5, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Bone metastases MicroRNA-141 (miR-141); miR-219 Cell culture and mouse studies suggest miR-141 and miR-219 could help prevent bone metastases. In cultured pre-osteoclasts, conditioned medium from...