18:47 , Nov 13, 2018 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Transgenics and knockouts miR-137-deficient mice could be used to screen therapies for schizophrenia, autism and other neuropsychiatric disorders. Mice with miR-137 knocked out in CNS and peripheral nervous system neurons recapitulated the learning and...
18:17 , Sep 27, 2017 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: SNPs SNPs near miR-137 could help predict the risk of schizophrenia. In neurons generated from patient-derived induced pluripotent stem (iPS) cells, genome-wide association studies (GWAS) identified associations between schizophrenia and about 100 SNPs flanking...
07:00 , Oct 27, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) MicroRNA-137 (miR-137); miR-181c; serine palmitoyltransferase long chain base subunit 1 (SPTLC1; LBC1); b-amyloid (Ab) Patient sample and mouse studies suggest miR-137 or...